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Edison Ovations announces final season

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David Bazemore
Ira Glass joins Monica Bill Barnes and Anna Bass in “Three Acts, Two Dancers, One Radio Host” Nov. 1-2. (High-res image available upon request.)

It’s been a good run, but eventually the house lights come up.

Since 1973, the Edison Ovations Series has brought nationally and internationally known performing artists to Washington University in St. Louis and to the community. But the 2014-15 season will be the Ovations’ last.

“All good things come to an end,” said Charlie Robin, executive director of Edison. “For 41 seasons, the Edison Ovations Series has provided trend-setting music, theater and dance artists with a receptive and adventurous audience.

“I’m very proud of everything we’ve achieved,” Robin said. “To help celebrate that legacy, for this final season, we’re welcoming a mix of old friends, a U.S. premiere, and unexpected new collaborations.

“This year will be our final statement,” Robin added. “We’re thrilled to share it. See you in the lobby.”

courtesy Photo
The Reduced Shakespeare Company tackles “The Complete History of Comedy (abridged) Nov. 14. (High-res image available upon request.)

The 2014-15 season

The season opens Sept. 27 with “Unveiled,” a one-person show by Chicago’s Rohina Malik, which explores the lives of Muslim women in post-9/11 America. Then, on Oct. 24 and 25, Edison welcomes Arabesque— the first private, neo-classical and contemporary dance company in Hó Chí Minh City, Vietnam — in their U.S. premiere, with “The Mist.”

On Nov. 1 and 2, “This American Life” host Ira Glass joins Monica Bill Barnes & Company for “Three Acts, Two Dancers, One Radio Host.” The inventive evening combines two art forms, dance and radio, that, as Glass jokingly puts it, “have no business being together.”

Concluding the fall season, on Nov. 14, is Edison favorite the Reduced Shakespeare Company in “The Complete History of Comedy (abridged).”


Cylla von Tiedemann
Doug Varone and Dancers in “Caruggi.” (High-res image available upon request.)

The spring semester opens Jan. 16 with “The Clothesline Muse,” a multidisciplinary performance — featuring six-time Grammy nominee Nnenna Freelon — that celebrates the unlikely links between domestic labor and community empowerment. New York’s Doug Varone and Dancers return for a pair of shows Jan. 23 and 24.

In February, Edison presents two events in WUSTL’s 560 Music Center. On Feb. 14, Broadway veterans Liz Callaway and Jason Graae combine love songs and comedy in “Happily Ever Laughter: A Valentine’s Party.” Then, on Feb. 21, Edison welcomes The King’s Singers, one of the world’s most celebrated vocal ensembles, for an evening of impeccable a cappella.

Ovations stalwart Scrap Arts Music, the Earth-friendly, Vancouver-based percussion ensemble, returns March 20.

Concluding the Ovations series, April 10 and 11, will be Giordano Dance Chicago. Founded in 1963 by native St. Louisan Gus Giordano, the distinguished company is both a pioneer of jazz dance and a leading advocate for its recognition as a distinctive American art form.

B. Ealovega
The King’s Singers, named for King’s College in Cambridge, England, jump the pond Feb. 21 for a one-night-only show at the 560 Music Center. (High-res image available upon request.)

ovations for young people

In conjunction with Ovations, Edison’s ovations for young people (oyp) will host three specially priced, all-ages matinees.

On Nov. 22, Jeff Boyer will present his one-man “Bubble Trouble,” an inventive mix of comedy, music and jaw-dropping bubble science. On March 21, oyp will welcome the percussionists of Scrap Arts Music. Giordano Dance will conclude the series April 11 with “Jazz Dance Beat … Then and Now.”

Anneke Janissen
Scrap Arts Music returns to Edison March 20. (High-res image available upon request.)

Tickets and information

Tickets to Ovations events are $36, or $32 for seniors; $28 for WUSTL faculty and staff; and $20 for students and children. Subscriptions are available at the basic level (three, four or five events at $32 per ticket) and at the premiere level (six or more events at $28 per ticket).

Ovations for young people tickets are $12 each. Subscriptions to that series are $27, or $24 for WUSTL faculty and staff.

Edison Theatre is located in the Mallinckrodt Center, 6445 Forsyth Blvd. The 560 Music Center is located in University City at 560 Trinity Ave. For more information or to order tickets, call the Edison Box Office at 314-935-6543; email edison@wustl.edu or visit edison.wustl.edu.

Edison programs are made possible with support from the Missouri Arts Council, a state agency; the Regional Arts Commission, St. Louis; and private contributors.

Gorman Cook Photography
Jazz dance pioneers Giordano Dance Chicago conclude the Ovations series April 10 and 11.



Two teams share $25,000 Discovery Competition top prize

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Projects to provide low-cost eyeglasses for people in the developing world and to develop a cell-death detector will share $25,000 to further develop their projects as winners of the 2014 Discovery Competition.

Projects to provide low-cost eyeglasses for people in the developing world and to develop a cell-death detector will share $25,000 in cash to further develop their projects as winners of the 2014 Discovery Competition. Washington University in St. Louis' School of Engineering & Applied Science created the competition in 2012.

In addition, two teams — The Rekord and Vaccine SmartBox — tied for third place.

One winning team is Envisioning Solutions, headed by Nathan Brajer, who earned a bachelor's degree this May in biomedical engineering, and Evan Madill, who earned a bachelor's degree this May in biology, in Arts & Sciences. The other is Viamor Research Solutions LLC, headed by Ben Berman, an incoming senior majoring in computer science; Ryan Charnov, who earned a bachelor's degree this May in entrepreneurship and economics/strategy in Olin Business School; Michael Harding, who earned a bachelor's degree this May in biomedical engineering and entrepreneurship; and Elizabeth Russell, who earned a bachelor's degree this May in biomedical engineering. 

Each team will receive $12,500 in cash and $2,500 in legal services from the Polsinelli law firm.

Dennis Mell, director of the Discovery Competition and professor of practice in electrical and systems engineering, said Envisioning Solutions and Viamor Research Solutions had identical scores from the judges, resulting in the tie.

The Rekord team, which designed a social media platform to allow for sharing, discovering and cataloguing of musical content across social networks, was awarded $7,500 in cash. The Vaccine SmartBox team, which created a battery-free refrigeration system for vaccines in developing countries, was awarded $5,000 in cash and $2,500 in legal services from Polsinelli.

“We are very proud of all of the students on all of the teams,” said Ralph S. Quatrano, PhD, dean of the School of Engineering & Applied Science. “It was clear to me and to all of the judges that the overall level of team development this year was significantly improved over last year. Each of the finalist teams had very creative proposals that will have impact in the developing world, in research and in entertainment.”

Envisioning Solutions will offer simple components that allow users to slide eyeglass lenses on and off of the frame until they determine their desired prescription strength. Optometrists are not always available in some developing countries. The World Health Organization estimates that about $270 billion in economic development could be created each year in developing countries by providing glasses to people who need them. The team has made 3-D printed prototypes and has sent market surveys to several nongovernmental organizations in developing countries, in which they plan to do field tests this summer.

Viamor Research Solutions has developed a novel solution to replace prior methods of testing whether cells are dying. The team developed an inexpensive technology that uses recent advances in digital holography, an imaging technique that relies on optical components and software to reproduce a 3-D rendering of the sample. The system will take images of about 100 samples in less than five minutes without destroying the cells. The product will be targeted to cancer and cell-biology research.

The Rekord team designed a free Web and mobile-based platform that allows artists, blogs, users and organizations to post, catalog and share music. The platform is integrated with YouTube and Soundcloud. 

Members of The Rekord team are Tarek Elhage, who earned a bachelor's degree this May in mathematics and economics and strategy; Julian Phan, who earned a bachelor's degree this May in systems science/engineering and finance; Michael Parker, who earned a bachelor's degree this May in entrepreneurship and marketing; Alexis Copithorne, an incoming senior majoring in communication design, in the Sam Fox School of Design & Visual Arts; Andy Garvin, who earned a bachelor's degree this May in business administration; Sam Donohue, an incoming senior majoring in systems science/engineering and computer science; Louis Wilson, an incoming junior majoring in systems science, engineering and computer science; and S.J. Lee, an incoming junior majoring in economics/strategy and finance.

The Vaccine SmartBox team created a way to prevent the loss of vaccines in the developing world. Often, vaccines are wasted after being exposed to unsafe temperatures during storage in villages where electricity is inconsistent or nonexistent. The team developed a temperature-precise, battery-free refrigeration system that does not rely on the power grid. 

The system uses an absorbent mineral called zeolite that soaks up water and cools while it evaporates. The team’s members are Anne Shellum, an incoming senior majoring in mechanical engineering and energy engineering; Andreea Stoica, an incoming junior majoring in mechanical engineering; Sarah Schubert, an incoming junior majoring in mechanical engineering; Justin Muste, an incoming junior majoring in biochemistry; Bo Huang, an incoming junior majoring in chemical engineering and finance; North Kay, an incoming junior majoring in electrical engineering; Kwok-Hao Lee, an incoming sophomore majoring in mathematics and economics; and Bryan Cai, an incoming junior majoring in computer science, mathematics and finance.

The School of Engineering & Applied Science launched the Discovery Competition in September 2012 to promote new and innovative discoveries to solve challenges or needs. The competition provides engineering undergraduate students the forum to explore their entrepreneurial interests with support from mentors, to use their creativity to develop solutions for real-world problems and to compete for financial resources that could help turn their ideas into businesses. The competition is an annual event and is funded by engineering alumni.

Teams were comprised of currently enrolled WUSTL undergraduate students, with at least one engineering student and at least one nonengineering student on each team.

For more information, visit engineering.wustl.edu/discovery.


 The School of Engineering & Applied Science at Washington University in St. Louis focuses intellectual efforts through a new convergence paradigm and builds on strengths, particularly as applied to medicine and health, energy and environment, entrepreneurship and security. With 82 tenured/tenure-track and 40 additional full-time faculty, 1,300 undergraduate students, 700 graduate students and more than 23,000 alumni, we are working to leverage our partnerships with academic and industry partners — across disciplines and across the world — to contribute to solving the greatest global challenges of the 21st century.



Cook receives Gloria White service award

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Mary Butkus/WUSTL Photos
Helen Kathleen Cook, PhD, academic coordinator for the Department of Anthropology, received the 2014 Gloria W. White Distinguished Service Award. Cook made remarks to Washington University in St. Louis employees gathered for the Danforth Campus Staff Day recognition ceremony May 19.

Academic Coordinator Helen Kathleen Cook, PhD, received the 2014 Gloria W. White Distinguished Service Award on May 19 for her work serving the students and faculty of the Department of Anthropology at Washington University in St. Louis.

The service award presentation is part of WUSTL’s annual Staff Day celebration, held May 19 to recognize and thank the nonacademic staff who keep the university running smoothly all year.

Chancellor Mark S. Wrighton presented Cook with the honor at the recognition ceremony in Edison Theatre. Wrighton called Cook, a 16-year veteran of WUSTL, a positive influence on the lives of both students and faculty.

“She keeps track of the smallest details, from a struggling student’s progress to helping new faculty members brainstorm about syllabus ideas to organizing faculty-student lunches and department-wide celebrations,” Wrighton told hundreds of WUSTL staff and faculty members. “She is certainly a key reason behind the growth and vibrancy of anthropology as a department.”

Cook said she was both honored and humbled by the recognition.

“I couldn’t do my job without all of the colleagues across campus who help me,” Cook said. “Here’s how it works for me — when I need to know something I don’t know, which happens frequently, I pick up the phone and I find out that answer. I get a cordial voice the other end of the line every time. These small conversations that we have form links among us, and links create relationships and community.

"At the other end of the line is a colleague who offers advice, information, a funny story when you need one, the odd bit of gossip and a sympathetic ear. It is a huge privilege for me to part of this university community, and I want to thank you all for being my warm and trusted colleagues.”

The Gloria W. White Distinguished Service Award comes with a $1,000 prize plus the opportunity to have the recipient’s nameplate added to 10 books in Olin Library. The award was established in 1998 and celebrates the legacy of Gloria White, a campus leader for some 35 years until her death in 2003. The award recognizes a nonacademic staff member for exceptional effort and contributions that have resulted in the betterment of the university.

Staff Day fun

The ceremony also included honoring employees who have worked at WUSTL for 10 or more years — including a couple as long as 45 years.

To see a full listing of employees honored for years of service, visit here.

Afterward, staff members enjoyed a barbecue lunch, and then an afternoon full of fun activities, from a bike ride or bingo to a walking tour of campus, or a game of softball or golf.

The day wrapped up with a drawing for assorted prizes — such as lunches or tickets to the movies, St. Louis Cardinals games and the grand prize of two plane tickets — plus Ted Drewes frozen custard.


Mary Butkus/WUSTL Photos
WUSTL employees enjoyed a variety of games and sports during the annual Staff Day celebration. Here, Mike Dunlap, of Accounting Services (left), and Mashiur Rahman play washers on Mudd Field. 

Kevin Lowder/WUSTL Photos
WUSTL employees (from left) Mark Bober, Josh Lawrence, Colin Odell, Glen Firns and Paul Hahn head out from Brookings Hall for a bike ride.

Mary Butkus/WUSTL Photos
The Spin Doctors, made up of staff members from various departments, won the softball tournament. Steve Givens, chief of staff for Chancellor Wrighton, holds the trophy.

Kevin Lowder/WUSTL Photos
Some staff members played bingo in Holmes Lounge, including (foreground, from left) Kelley Green, Tanya Sawyer and Pam Hinrichs, all of the Office of Sponsored Research Services.


Grad student co-directs film about the game of Go

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All Go players know about the Blood-Vomiting Game, a four-day-long game of Go played in Japan in 1835. The match featured three “ghost moves” allegedly brought to the victorious player by ghosts, and ended with the losing player vomiting blood onto the board and collapsing.

All the spectators saw was two men sitting on either side of a board; but within their minds, the players were locked in struggle no less violent because it was completely silent.

One hundred eighty years later, two young Go players at Brown University, Cole Pruitt and Will Lockhart, gambled that they would be able to make an audience feel that hidden intensity, tension — and even violence — when they decided to make a documentary film about Go.

The film, called "The Surrounding Game," is now in post-production, said Pruitt, who is currently a graduate student in chemistry at Washington University in St. Louis.

Go belongs to the class of no-luck board games, along with chess and Othello. Two players attempt to enclose as much space as possible by placing black or white stones on the intersections of a 19-by-19 grid. The rules are simple enough that a child can learn them in minutes, but the game is also — paradoxically — complex enough that players must study for years to become professional Go players, a lifetime title accorded to only the strongest players.

The film follows two of America's top young players as they compete to win professional rank. Andy Liu, a Chinese-born American with very little formal training, has become one of the strongest players in North America, developing his own style by playing 20 games a day. Brooklyn-born Ben Lockhart (Will’s younger brother) has chosen to make Go his career and now lives in Korea, where he studies at a professional Go school.

Implicit in the players' choices is a dilemma. Can a game this subtle and difficult, which has been pursued as a fine art in Asia for millennia, be transplanted to America, which does not have the culture or the training system to support it, and favors entertainment that is more gladiatorial than cerebral?

Courtesy photo
Andy Liu and Evan Cho, a former Korean yunguseng (Go academy student) who is one of the strongest amateur players in the U.S., play Go on Chimney Rock in North Carolina in 2012.

 


One of four ancient Chinese arts

Go, invented more than 2,500 years ago, is one of the four ancient Chinese arts, together with painting, calligraphy and music.

Although Go was invented in China, Pruitt explains, its culture is rooted in medieval Japan, where talented disciples devoted their lives to Go by entering one of four rival Go houses, which were led by the strongest masters of the era.

Today, Chinese and Korean students as young as 5 begin training in special Go schools with the aim of becoming a Go professional. To have a chance of going pro, they must abandon a high-school education and study nothing but Go for years on end. Among the game's elite professionals, international tournaments offer hundred-thousand-dollar prizes and are simulcast on television.

Outside of East Asia, the story is very different. The American Go Association, founded by chess master Edward Lasker and friends in 1935, is one of the oldest Western Go associations, but it never has supported a professional Go system.

At the climax of “The Surrounding Game,” the American Go Association holds its first professional-certifying Go tournament, with both Liu and Ben Lockhart competing to become the first Western-certified pro.


How to Kickstart a film

Making a film is an education in itself, said Pruitt. You learn a bit about running a business, production, grant writing, interviewing … a little bit of everything.

“The way this got started was that Will and I were invited to travel to China in 2011 as part of a college Go delegation, a trip hosted by the ING (Ing Chang-ki) Foundation, a philanthropic organization that promotes Go and runs the world’s largest tournament,” said Pruitt.

The next year, they were returning by bus from a Go tournament when Will Lockhart, many of whose family members work in the film industry, said he had been thinking about making a film about Go.

Pruitt was immediately enthusiastic, and a few weeks later, they asked the ING Foundation for enough funding to film a three-minute trailer they could shop around to see if there was any interest. They filmed the trailer and launched a Kickstarter campaign, beating their funding goal by $10,000 as word of the documentary spread in the Go community. “So we were off to the races,” Pruitt said.

Pruitt, who already had been admitted to graduate school at WUSTL, asked for and was granted a gap year to work on the film.

Courtesy photo
A gathering of some of the film team (from left): Kim Chaelim, a field producer/interpreter during shooting in Korea and a former Korean yunguseng (Go academy student); Will Lockhart, co-director; Lee Sedol, the world's top-ranked player;, Cole Pruitt, co-director; and Nik Gonzales, second camera.

 

Eighteen months later, the project has gathered 180 hours of footage filmed in China, Korea, Japan, the U.S. and Canada. Just this spring, the filmmakers won a film pitch contest at the American Documentary Film Festival in Palm Springs, Calif., bringing them one step closer to putting the finishing touches on the film.

“Originally, we had planned for a small production that would just take a year. But now it has grown into a feature-length film that we think will introduce Go to the U.S. and make a splash,” Pruitt said.

The filmmakers hope to premiere “The Surrounding Game” in 2015 at several national film festivals, make it available online through digital download and DVD and, if possible, screen it in theaters nationwide.

What makes Go special?

Pruitt didn’t really learn the game until spring of his junior year at Brown, when he stayed at school after the term ended to finish a project. With his evenings free, he decided to devote them to learning Go. “A week later,” he said, “I knew that I would be playing Go for the rest of my life.”

What is it about Go that inspires this kind of passion?

Game theorists would say it is a very clean game. “It’s a game of perfect information,” said Pruitt. “There’s no luck, there’s no dice, you can’t hide behind the cards or anything like that. Everything’s out in front of you, and you have enough time to make decisions between turns.”

“Since there are only four simple rules, it doesn’t sound like play should be complicated,” Pruitt said. 


To learn to play Go, try the online interactive problems at these sites:
The Interactive Way to Go
Sensei's Library
The Surrounding Game
American Go Association

But if Go is one of the simplest games, it is also one of the most complex.

There are several reasons for its depth. The dimensions of the board are unusually large (stones can placed at any of 361 intersections), so the number of possible sequences of moves quickly increases and then explodes. In fact, the number of possible games of Go far exceeds the number of atoms in the observable universe, ensuring that individual games are never played more than once.

Another reason Go is challenging is that intermediate positions are notoriously hard to evaluate. It can be difficult to tell whether a group of stones is surrounding or being surrounded and which player is ahead. In chess, by contrast, computers can assign each piece a numerical value and add up each piece on the board to 'measure' the favorability of a position.

During a Go game, good players can look ahead more than 30 moves, and they rely on this analytical ability to win local battles involving small groups of stones. But to evaluate the full board and their global position, players rely on the intuitive and creative parts of the brain.

This aspect of the game has rubbed off on its vocabulary. Players look for “ladders” and “nets,” “living” and “dead” groups, “dumplings” and “stone towers.” Because hidden sequences may become favorable much later in the game, players use the Japanese term aji, or flavor, to describe latent possibilities available to key stones.

Because of its complexity and subtlety, a game of Go can become a virtual world in which players can immerse themselves, losing track of the world around them. “Many people play Go online,” said Pruitt. “That’s how they get their fix. They have this place, this engaging alternative world that they can enter at will. That can be very addictive.”

An endless fascination

But is living in an alternative world an acceptable way to spend your life in America? What if you’re earning “Linden” dollars building wings with animation software for avatars in "Second Life"? What if you’re a mathematician? What if you’re a pure mathematician? What if you’re a string theorist? What if you’re a poet? What if you’re a poet who never has been published?

“In the U.S., if you spend your life playing a game, what are you? A freak? A sad shell?” said Pruitt. “In Japan, a life spent playing Go is not a life wasted; it’s a life spent cultivating an art. In some ways, its one of the highest callings you can have.”

That tension, he said, is central to “The Surrounding Game.”





Gerald Early’s remembrances of Maya Angelou

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WUSTL PhOTos
Internationally acclaimed author and poet Maya Angelou signs copies of her books after her April 1, 1981, speaking engagement in Washington University’s Graham Chapel. She would give two more talks in Graham Chapel within the coming decade.

Noted American essayist and culture critic Gerald L. Early, PhD, has fond remembrances of when he introduced Maya Angelou before one of her three speaking engagements at Washington University in St. Louis.

It was 1984, and Early was a new assistant professor of English and of African and African-American studies, both in Arts & Sciences at the university.

He was asked to introduce the legendary poet, author, actor and civil rights activist when she spoke Feb. 8 during the university’s Assembly Series lecture program in Graham Chapel. Angelou presented a reading of her work and provided commentary for the second annual Chimes (junior honorary society) Lecture.

WUSTL Photos
Of Maya Angelou, pictured here speaking in Graham Chapel in 1981, WUSTL acclaimed poet Carl Phillips said: “Maya Angelou was a living testimony to the power to overcome hardship by believing it possible. ‘I Know Why the Caged Bird Sings’ established her as a voice for the oppressed and traumatized, in particular, but for women of color especially. Her refusal to give in to difficulty — her insistence on using struggle as a means of gaining strength — has inspired several generations. It’s an inspiration that will surely continue to resonate with readers everywhere.”

Early, now the Merle Kling Professor of Modern Letters in Arts & Sciences at WUSTL, recalled, “I was completely intimidated by her. She was a very larger-than-life person, carried herself like something of a movie star.

“At any rate, she gave a fantastic presentation, combining her literary and theatrical skills seamlessly. Afterwards, she came up to me and told me she liked my introduction. ‘It was worthy of me,’ is exactly what she said,” Early recalled.

“I did not mind her egotism at all. I thought she earned the right to be sort of Norma Desmond-like. I felt pretty pleased with myself because she liked what I said about her. In fact, I was very happy with myself the rest of that day.”

Angelou, a native St. Louisan who died May 28, 2014, at the age of 86, first spoke at Washington University on April 1, 1981, when she delivered the Martin Luther King Jr. Symposium keynote address. Her talk was titled “The Many Facets of Maya Angelou.”

She also delivered a third Assembly Series lecture in Graham Chapel Feb. 22, 1990, for the Association of Black Students/Council of Students of Arts & Sciences Lecture. Her talk was part of a series of events at the university commemorating Black History Month.

“I encountered her one or two other times at meetings where I really did not have any interaction with her, but her presence was always something grand,” Early said. “I never met a writer who had such a commanding sense of herself.”

Angelou was the author of more than 30 best-selling titles in verse, fiction and nonfiction, including her first autobiography, “I Know Why the Caged Bird Sings,” which earned a National Book Award nomination.

“‘I Know Why the Caged Bird Sings’ will always be one of the great African-American autobiographies ever written, one of the great American autobiographies,” Early said.

“She was one of the few writers, black or white or anything else, who had both a huge popular audience, but also was respected by the literati for her autobiographies, particularly ‘I Know Why the Caged Bird Sings.’

“Her life was quite an achievement.”



Pollak attends White House meeting to discuss economics of the family

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In preparation for an upcoming summit on working families, Robert Pollak, PhD, an expert on family economics at Washington University in St. Louis, recently attended a meeting at the White House with other academic leaders and senior administration officials. They gathered to discuss the implications of demographic and other changes for 21st-century workplaces.

Pollak
Pollak is the Hernreich Distinguished Professor of Economics in Olin Business School and in Arts & Sciences.

Pollak joined 10 other researchers to discuss how the United States can best meet the current needs of families and employers, concentrating on changing patterns of childbearing, cohabitation and marriage and the resulting need for greater workplace flexibility.

"The meeting provided senior administration officials with an overview of current research on changes in American families and work that have taken place over the last 50 years," Pollak said. "These changes include increases in women's education, which now surpasses that of men, and increases in women's work outside the home — women now make up about half of the U.S. workforce. The discussion focused on the ways in which workplaces have adapted or failed to adapt to these changes."

The meeting was designed to engage in a research-oriented discussion to inform policymakers’ thinking ahead of the White House Summit on Working Families, which will take place June 23. The summit will convene business and labor leaders, economists, policymakers, advocates and citizens to discuss policy solutions that can make a difference in the lives of working families and ensure America's global competitiveness in the coming decades.

Pollak is co-author of the influential paper "Cohabitation and the Uneven Retreat from Marriage in the U.S., 1950-2010." He also has published on family decision-making, power couples and household time allocation. His paper "Family Proximity, Childcare, and Women's Labor Force Attachment" recently was published in the Journal of Urban Economics.



Awards bring two faculty members new opportunities

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Faculty members Darren Dochuk, PhD, and Nancy Reynolds, PhD, will be delving into new experiences thanks to awards received this spring.

Dochuk

Dochuk, an associate professor of history and a faculty member of the John C. Danforth Center on Religion & Politics, will be in China for two weeks in June. He received a 2014 China Residency to teach a weeklong seminar on the history of U.S. religion at the American Studies Center at Beijing Foreign Studies University.

About 35 participants — including professors, master’s students and doctoral candidates — will be enrolled in the seminar. These participants were chosen from a large pool of applicants from more than 20 major Chinese universities.

Dochuk said his goal is to teach them the broad scope of U.S. religious history in ways that equip them for their own research and teaching of American history.

Three U.S. scholars will participate in this year’s seminars in China. As part of the exchange program, three Chinese scholars will do research in the United States at select universities. The Organization of American Historians and the American History Research Association of China sponsor the seminars and residency. The Ford Foundation funds the residency.

For more information on the program, visit here

Reynolds
Reynolds received a New Directions Fellowship from the Andrew W. Mellon Foundation for her project, “Heat: Recent Egyptian Histories.” She is an associate professor of history; of Jewish, Islamic and Near Eastern languages and cultures; and of women, gender and sexuality studies. 

New Directions Fellowships help faculty members in the humanities acquire systematic training outside of their own areas of interest. The fellowship will allow Reynolds to pursue formal training in environmental studies, as well as botany, zoology and geology, to undertake future research on the environmental history of Egypt.

New Directions Fellows receive the equivalent of one academic year’s salary, two summers of additional support, and tuition or course fees associated with the fellow’s training programs.

For more information on the New Directions Fellowship, visit here. 




As the heat of summer settles on St. Louis, here’s a gust of cold air from Antarctica

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1 | 2 | 3





Jan. 13, 2014: After 30 hours of flying and running around airports,  I made it to Christchurch, New Zealand, the jumping-off point for much of the U.S. Antarctic Program. McMurdo Station, which will be our home base of the next month, is on the southern tip Ross Island, just off the coast of Antarctica and joined to it by ice.



McMurdo via helicopter. The dark brown buildings on the left are dorms, the blue building is the galley, and the gray many-armed building on the right is the science lab. Working out of McMurdo (population 886 today; just below freezing) is very different from last year working out of the South Pole Station (population around 100; way, way below freezing). Here in McMurdo, there is quite a bit to do — hiking trails, animal watching, sports equipment rentals, two bars, a coffee/wine house, band performances, lounge and pool rooms in every dorm, and so much more. At the South Pole, for leisure time you could read in your room, read in the library, or read in the lab.


When weather permitted, my team flew by helicopter or by a small twin-engine plane to the remote locations of our seismic stations. Here I am sporting a super-fashionable helicopter helmet.

Jan. 29, 2014: Today, I finally made it to the field! This is a MILR (seismic name)/IGGY (GPS name) station near Miller Range. There was quite a bit of work to be done. We replaced most of the instrumentation and moved the seismic sensor from the rock to a hole in the snow in an attempt to make it less noisy. The noise might have been due to wind buffeting the sensor’s enclosure, or, possibly, to the rock shifting. 


One day, standing outside the science building looking across McMurdo Sound, I noticed that the mountains appeared to have vertical stripes. The more I looked, the more it appeared the base of the mountains was reflected upward, not downward in the water, as you might expect. I was told this is an unusual type of mirage called a "Fata Morgana.” They’re named for the sorceress Morgan Le Fay because the mirages often seem to create the crenellated turrets of fairy castles at the horizon.


A Fata Morgana created by a thermal inversion near the horizon, with warm air overlying cold air (typically, warm air is closest to the ground). Light paths are bent by these thermal layers, and your eye perceives the light as having originated from a different location.

Part 2 of Aubreya Adams' photo album




Obituary: Albert Baernstein, professor emeritus of mathematics, 73

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Baernstein

Albert Baernstein II, professor emeritus of mathematics in Arts & Sciences at Washington University in St. Louis, died at his home on Tuesday, June 10, 2014. He was 73.

He came to Washington University in 1972, earning the position of professor of mathematics in 1974. He taught at the university for 40 years, becoming professor emeritus in 2012.

For many years, he could be seen daily, in all weather, striding from his home in University Heights to his office in Cupples I Hall, at first accompanied by his beloved dog, Porterhouse, and later by another big mutt, Sadie.

Baernstein earned a bachelor’s degree from Cornell University and a master’s and PhD from the University of Wisconsin-Madison. He taught at Syracuse University briefly before moving to WUSTL.

“He was a highly respected mathematician, with an international reputation in the fields of complex analysis and potential theory,” said his colleague John McCarthy, the Spencer T. Olin Professor in Arts & Sciences. “He had a special affinity for symmetrization problems – roughly speaking, showing that the most symmetric arrangement corresponds to the lowest energy. In 1972, he invented something now called the Baernstein Star Function and used this to solve several open problems in mathematics, including the difficult Edrei spread conjecture.

“Al and his wife, Judy, were very warm and generous people,” said McCarthy. “There was a constant stream of mathematical visitors to the university and Al and Judy would invite the entire department over to their house for a party; this set the tone that made the Wash. U. mathematics department one of the friendliest in the world.

“On one occasion, a Russian mathematician, who had come to visit the University of Missouri, was badly injured when the bus from the airport to Columbia crashed. Although the Baernsteins did not know the man, and he spoke almost no English, Al and Judy took him into their home for weeks while he convalesced to the point of being able to travel home again.”

In his family, he was notorious for his precision of memory and measurement. As a 5-year-old, he entertained his parents’ friends by calculating the day of the week for any given date in the century. As an adult, he entertained his children by recalling the details of any rest stop on any past family vacation, including the price of gas and whether the motel pool was open.

Manual labor proved more challenging: his lifelong inability to perform such mundane tasks as peeling an orange, inflating a bicycle tire or operating a pepper mill afforded endless amusement to his family.

He loved bad puns and limericks, and improvised them at every turn, as well as dark ale, hot curry and Wagner.

Survivors include his wife of 52 years, Judy (Haynes) Baernstein; two daughters, Prudence Renee (Wietse de Boer) of Oxford, Ohio, and Amy (Melanie Tratnik) of Seattle; four grandchildren: Sylvia and Arthur de Boer of Oxford, Ohio, and Cleo and Nora Baernstein of Seattle; and a sister, Alice Kirby, of Augusta, Ga.

In lieu of flowers, donations may be made to the University City Public Library, where Al was a longtime patron, or to a library of your choice.




Humans have been changing Chinese environment for 3,000 years

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Known as the “cradle of Chinese civilization,” the Yellow River was the birthplace of the prosperous northern Chinese civilizations in early Chinese history. However, the Yellow River is also referred to as “China’s Sorrow” because of its frequent and devastating flooding.
For thousands of years, Mother Nature has taken the blame for tremendous human suffering caused by massive flooding along the Yellow River, long known in China as the “River of Sorrow” and “Scourge of the Sons of Han.”

Now, new research from Washington University in St. Louis links the river’s increasingly deadly floods to a widespread pattern of human-caused environmental degradation and related flood-mitigation efforts that began changing the river’s natural flow nearly 3,000 years ago.

WUSTL archaeologist T.R. Kidder excavates at Sanyangzhuang, an ancient, flood-buried community known as China's Pompeii.
“Human intervention in the Chinese environment is relatively massive, remarkably early and nowhere more keenly witnessed than in attempts to harness the Yellow River,” said T.R. Kidder, PhD, lead author of the study and an archaeologist at Washington University.

“In some ways, these findings offer a new benchmark for the beginning of the Anthropocene, the epoch in which humans became the most dominant global force in nature.”

Forthcoming in the Journal of Archaeological and Anthropological Sciences, the study offers the earliest known archaeological evidence for human construction of large-scale levees and other flood-control systems in China.

A catastrophic flood

It also suggests that the Chinese government’s long-running efforts to tame the Yellow River with levees, dikes and drainage ditches actually made periodic flooding much worse, setting the stage for a catastrophic flood circa A.D. 14-17, which likely killed millions and triggered the collapse of the Western Han Dynasty.

“New evidence from China and elsewhere show us that past societies changed environments far more than we’ve ever suspected,” said Kidder, the Edward S. and Tedi Macias Professor in Arts & Sciences and chair of anthropology at WUSTL. “By 2,000 years ago, people were controlling the Yellow River, or at least thought they were controlling it, and that’s the problem.”

Kidder’s research, co-authored with Liu Haiwang, senior researcher at China’s Henan Provincial Institute of Cultural Relics and Archaeology, relies on a sophisticated analysis of sedimentary soils deposited along the Yellow River over thousands of years.

Locator Map: The Yellow River Vallley of China, with Box A identifying the flood plain regions researched in this study.The star in Box B is the location of the Anshang and Sanyangzhuang sites. The approximate extent of the Loess Plateau is indicated by shading. VIEW LARGER>

It includes data from the team’s ongoing excavations at the sites of two ancient communities in the lower Yellow River flood plain of China’s Henan province.

The Sanyangzhuang site, known today as “China’s Pompeii,” was slowly buried beneath five meters of sediment during a massive flood circa A.D. 14–17, leading to exceptional preservation of its buildings, fields, roads and wells.

The Anshang site, discovered in 2012, includes the remains of a human-constructed levee and three irrigation/drainage ditches dating to the Zhou Dynasty (c. 1046–256 BC). 

Researchers examined about 50 vertical feet of exposed soil layers at the Anshang site, carefully cleaning sections of a quarry wall to reveal patterns of sedimentary deposits dating back about 10,000 years. Nearly a third of this 10,000-year cross-section has been deposited in the last 2,000 years, indicating that the rate of deposit has steadily increased at a pace that mirrors the expansion of human activity in the region.

The southwest corner of the brick quarry dig site at Anshang shows remnants of the bank/levee in the sedimentary record. VIEW LARGER>

While ancient levees may be difficult to spot with an untrained eye, geoarchaeologists employ an array of precise analytic tools to confirm a site’s sedimentary history. Soil layers are identified by coloration and tested for physical and chemical alterations linked to human activity. Timeframes are identified through radiocarbon dating of freshwater snail shells and other organic soil matter.

“Thin microscopic sections of dirt samples show organization of soil grains, revealing whether an earthen structure was human-built or laid down as part of a natural sedimentation process,” Kidder said. “Our analysis clearly shows that these levees are not naturally formed berms, but are indeed artificially created through the work of humans.”

Kidder’s research suggests the Chinese began building drainage/irrigation canals and bank/levee systems along the lower reaches of the Yellow River about 2,900–2,700 years ago. By the beginning of the first millennium A.D., the levee system had been extended much farther up river, lining the banks for several hundred miles, he estimated.

The levees were built in part because of increasing erosion upstream, which was caused by more intensive agriculture and the expansion of the growing Chinese civilization. The sedimentary record shows a vicious cycle of primitive levees built larger and larger as erosion increased and periodic floods grew more widespread and destructive.

Boxed section of Image A shows the first stage of a bank/levee exposed in the excavation at Anshang. Image B offers a closer view of the boxed section showing mixed and loaded/rammed sediments near the base of the bank/levee. VIEW LARGER>

“Our evidence suggests that the first levees were built to be about 6-7 feet high, but within a decade the one at Anshang was doubled in height and width,” Kidder said. “It’s easy to see the trap they fell into: building levees causes sediments to accumulate in the river bed, raising the river higher, and making it more vulnerable to flooding, which requires you to build the levee higher, which causes the sediments to accumulate, and the process repeats itself. The Yellow River has been an engineered river — entirely unnatural — for quite a long time.”

Help for understanding climate change's effects

Kidder, an authority on river basin geoarchaeology, has gathered data from the Yellow River excavation sites over the last five summers. He also conducts similar geoarchaeology research along the Mississippi River at a Native American site called Poverty Point in Louisiana.

He argues that geoarchaeology — a relatively new science that combines aspects of geology and archaeology — offers the potential to make dramatic contributions to our understanding of how climate change and other large-scale environmental forces are shaping human history.

While there are many theories behind the fall of the Western Han Dynasty, Kidder’s research suggests human interaction with the environment played a central role in its demise. In this study, he offers a big-picture explanation for how a complex mix of well-intentioned government policies and technological innovations gradually led the dynasty down a disastrous path of its own making.

The Yellow River, he argues, had existed for eons as a relatively calm and stable waterway until large numbers of Chinese farmers began disturbing the fragile environment of the upper river’s Loess Plateau. Built up over the ages by wind-blown sands from the nearby Gobi Desert and Qaidam Basin, the plateau has long boasted some of the world’s most erosion-prone soils.

As early as 700 B.C., Chinese authorities were encouraging peasant farmers to move into remote regions of the plateau, citing the need to feed a large and growing population while establishing a buffer of human settlement against the threat of nomadic invaders along its northern border. Construction of The Great Wall swelled populations still further.

Meanwhile, new iron-making technologies vastly increased the effectiveness of plows and other farm tools while spurring rapid deforestation of timber used in iron refining. Widespread erosion in the river’s upper regions caused it to carry incredibly heavy loads of sediment downstream where deposits gradually raised the river bed above levees and surrounding fields. 

Implications for modern river management

Slowly, over thousands of years, human intervention began to have a dramatic impact on the river’s character. Periodic breaches of the levee system led to devastating floods, with some shifting the river’s main channel hundreds of miles from its initial course.

Map showing historically identified courses of the Yellow River and its historic mega-deltas. The 1938–1947 course evolved after the dykes were destroyed to (unsuccessfully) prevent Japanese forces from advancing across the Central Plains. VIEW LARGER>

A census taken by China in A.D. 2 suggests the area struck by the massive A.D. 14-17 flood was very heavily populated, with an average of 122 people per square kilometer, or approximately 9.5 million people living directly in the flood’s path.

“The misery and suffering must have been unimaginable,” Kidder said.

Historical accounts indicate that communities hit by the flood were soon in complete disarray, with reports of people resorting to banditry to obtain food and stay alive. By A.D. 20-21, the flood-torn region had become the epicenter of a popular rebellion, one that soon would spell the end of the Western Han Dynasty’s five-century reign of power.

“The big issue here is that human beings clearly changed the environment, and that these changes had real consequences for human history,” Kidder said. “It happened in the past and can happen again.”

While the research offers new insight into Chinese history, it also has interesting implications for modern river management policies around the globe, such as those causing similar flooding problems along the Missouri and Mississippi rivers in the United States.

“To think that we can avoid similar catastrophe today due to better technology is a dangerous notion,” he said. “When in doubt, bet on Mother Nature because physics will win every time.”

“Human-caused environmental change is nothing new,” Kidder said. “We’ve been doing this for a very long time, and the magnitude of change is increasing. Unlike ancient China, where human mistakes devastated a single river valley, we now have the technology to make mistakes that can cause devastation on a truly global scale.”

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Editor's note: Research maps and images courtesy of the Journal of Archaeological and Anthropological Sciences.



PARC wins renewed funding for photosynthetic research

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Sid Hastings/WUSTL Photos
Bob Blankenship, PhD, director of PARC and the Lucille P. Markey Distinguished Professor in Arts & Sciences at Washington University in St. Louis, announcing at an all-hands meeting June 18 that the center had just received funding for the next four years.

 

When Robert Blankenship, PhD, stood up during the annual all-hands meeting of the Photosynthetic Antenna Research Center (PARC) at Washington University in St. Louis, he immediately had the attention of everyone in the room.

A decision about renewal funding was overdue, rumors had been flying and Blankenship, PARC’s director, wasn’t on the June 18 meeting agenda for that time slot.

He said quite simply that he had just received an email from the Department of Energy (DOE) saying that the agency was pleased to inform him that PARC’s proposal for a second round of funding as an Energy Frontier Research Center (EFRC) had been successful.

After the roar of applause had died down, he added that the award was for $3.6 million for a period of four years, for a total of $14.4 million.

Everyone in the room knew that PARC was well regarded in the scientific community, but they also knew in most federal agencies the funding rates were around 10 or 15 percent. The competition for this round of funding was very stiff.

In 2009, the DOE had funded the creation of 46 EFRCs to lay the scientific groundwork necessary to meet the global need for abundant, clean and economical energy.

Only about half of the 46 centers were funded in the second round, although 10 new ones were added for a total of 32 awards. Those 32 projects were selected from more than 200 proposals.

“I want to personally thank everybody in this room because all of you contributed to making this a success. We couldn’t have gotten the renewal without a tremendous amount of hard work and fantastic science from all of you,” said Blankenship, who is a professor of chemistry and of biology.

Capturing the sun’s energy output

The centers selected for the second round of funding will help lay the scientific groundwork for fundamental advances in solar energy, electrical energy storage, carbon capture and sequestration, materials and chemistry by design, biosciences and extreme environments.

PARC’s goals are to understand the basic scientific principles that govern solar energy collection by photosynthetic organisms and to use this knowledge to fabricate more efficient biohybrid and bio-inspired systems to drive chemical processes or generate photocurrent.

Natural photosynthetic systems consist of two parts: antennas that collect solar photons and reaction centers that transform the easily dissipated light energy into the more durable form of charge separation that can then be used to do work.

The scientists are broadening their goals for PARC 2. PARC 1’s goal was to increase the efficiency of light harvesting antennas. In PARC 2, the scientists will continue their work on the antennas but will also start looking at energy delivery at the reaction center interface and reaction center design.

“It’s really gratifying to see the high level of support that DOE has provided for solar-related research,” said Jonathan Lindsey, a PARC principal investigator from North Carolina State University.

“Young students coming into my laboratory are very excited and motivated by the chance to make a real contribution to something that they see as being a very important part of their lives and their own children’s lives,” said Christopher Moser, a PARC principal investigator from the University of Pennsylvania.

‘Biggest legacy will be cadre of scientists’

It was just by coincidence that the funding announcement coincided with the PARC all-hands meeting, which had been planned for almost a year. But as one of the participants said, to have the renewal announced when everyone was together was a thrill.

Despite the high level of excitement at the announcement, it was remarkable how often the conversation among the older scientists turned to the younger scientists, the graduate students and the postdoctoral fellows.

“In the end, one of the outcomes that will be most important is to give our graduate students and postdocs an opportunity to work in a collaborative center where they can do things that they would normally never be able to do on individual research grants,” said Dewey Holten, PhD, associate director of PARC and a professor of chemistry at WUSTL.

“Perhaps our biggest legacy will be this cadre of scientists that we will have trained here at PARC who will go on and solve these pressing problems. We probably won’t solve all those pressing problems in four more years (laughter), but we will make progress,” Blankenship said.

Richard Cogdell, a PARC principal investigator from the University of Glasgow in Scotland, agreed, and added, “But we will have built a community that will solve them over the next 10 to 20 years.”

Washington University is the host and administrative center for PARC, whose partners include investigators from the Los Alamos National Laboratory, North Carolina State University, Northwestern University, Oak Ridge National Laboratory, Sandia National Laboratories, University of California-Riverside, University of Glasgow, University of New Mexico, University of Pennsylvania, University of Sheffield in England, Princeton University, University of Illinois at Urbana-Champaign and Penn State.




How repeatable is evolutionary history?

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Genevieve Hay
Evolutionary biologist Ken Olsen and Cynthia Vigueira, then a postdoctoral associate in the Olsen lab, examine white clover in the Washington University greenhouse. One morph of this species of clover releases cyanide gas to discourage nibbling.

 

Writing about the weird soft-bodied fossils found in the Burgess Shale in the Canadian Rockies, paleontologist Stephen Jay Gould noted that of 25 initial body plans exhibited by the fossils, all but four were quickly eliminated. If we rewound the tape, he asked, and cast the dice once more, would the same four body plans be selected? He thought it unlikely.

We can’t repeat the Burgess Shale experiment, but Washington University in St. Louis biologist Ken Olsen, PhD, says there are other ways to ask whether evolution is repeatable. One is to look at related species that have independently evolved the same traits and ask if the same genes are responsible and, if so, whether the same mutations led to the trait.

Looking at 27 species in the genus Trifolium (clovers), Olsen, an associate professor of biology, showed that six of them displayed what is called a balanced polymorphism. In some environments, natural selection favors plants that release hydrogen cyanide to discourage nibbling, while in others, plants that do not release cyanide are favored. The polymorphism evolved independently in each of the six species.

Often, we think of evolution as driven by chance mistakes in DNA replication, some of which produce novel traits. But in this case, chance played little part. The clover species are in a sense predisposed to develop this trait.

“We see exactly the same genetic mechanism — and it’s kind of a weird mechanism — underlying the repeated evolution of the acyanogenic (cyanide-less) trait in different clover species,” Olsen said.

The plants that don’t make cyanide have deletions in their genomes in the spots where the required genes would normally be found. It’s not that the gene is mutated; it’s missing entirely.

“This is interesting,” he said, “because it gets at the question of how constrained evolution is. The more it is constrained, the more predictable it is, but also the less adaptive flexibility there is.”

“If you look at life on the planet, there’s such an incredible diversity of life forms and traits that we tend to think anything goes,” Olsen said. “But when we look more carefully, we see there are constraints. There aren’t any living species of limbed vertebrates with six toes, for example; it’s five toes or fewer.”

The work appears in a special issue of Philosophical Transactions of the Royal Society B published online June 23. The issue honors the scientific contributions of Leslie D. Gottlieb, an early advocate of the use of biochemical and molecular data to study plant evolution.

The cyanide bomb
Scientists have known that some forms of white clover release hydrogen cyanide for more than a century. They also quickly realized that white clover is polymorphic for the trait, meaning the species includes both cyanogenic and acyanogenic morphs.

This polymorphism has been the subject of a large number of studies to determine both the distribution of the two morphs and the nature of the selective forces responsible for maintaining the polymorphism.

Plants that release cyanide have a two-chemical “cyanide bomb” that is activated only when plant cells are crushed and the chemicals come in contact. Stored in the central vacuole of the plant cells are cyanogenic glucosides: sugar molecules with an attached cyanide group. In the plant cell’s wall, an enzyme called linamarase can cleave the bond attaching the cyanide to the sugar.

When a slug, snail or chewing insect — the major predators on clover in the seedling lifestage — crushes the tender cells, the enzyme cleaves the cyanide, which combines with hydrogen to form gaseous hydrogen cyanide.

Many plants have this ability. It’s what makes peach pits and apple seeds poisonous, for example. “In the case of clover, cyanide release probably doesn’t kill herbivores outright,” Olsen said. “ It’s more likely to just taste terrible — so it serves as a feeding deterrent. The level of cynanide released is much higher in other species, such as birdsfoot trefoil (the yellow-flowered plant that blooms along highways in June). In that case, it probably could kill them.”

Ken Olsen
The clover genus Trifolium is surprisingly varied. Of the clover species shown here, T. repens (bottom right), commonly known as white clover, and T. isthmocarpum (middle left), a salt-tolerant species known as Moroccan clover, include both cyanide-producing and cyanide-less plants, although some of the other species have one of the two genes needed to synthesize cyanide.

 

But white clover plants that make cyanide don’t grow everywhere. You’re much more likely to find them in warmer climates than in cold ones. In New Orleans, for example, 85 percent of the white clover plants growing in lawns might be cyanogenic, while in Wisconsin, only 10 percent might be.

A working hypothesis, Olsen said, is that in cooler climates, there are fewer herbivores around. “Since making these compounds is energetically expensive, plants that don’t spend their resources making them have a competitive advantage in the cooler climates.”

Just press DELETE
Making the bomb requires two genes that are located in different parts of the clover genome. One of these genes controls the synthesis of the cyanogenic glucosides, and the other encodes the linamarase protein.

What happens when a cyanide-less morph pops up, Olsen said, is that one of these genes is deleted. “We see independent gene deletions occurring repeatedly in multiple species. So lots and lots of gene deletion.”

This is not the “normal” way we think of adaptive variation occurring, Olsen said. Most of the time, random mutational changes affect one or a few nucleotides within one gene, which might convert one amino acid to another, which might alter a protein’s function. So the changes are random and incremental. Instead, in this case, the entire gene disappears.

In the clover genus, something is making it easier for adaptive variation to arise through gene deletions than through simple mutations, Olsen said.

He thinks that “something” might be repetitive nucleotide sequences (repeats) near the cyanide bomb genes. In that case, chromosomes align to the “wrong” repeat when they pair during meiosis and swap genetic material. Unequal swaps caused by the misalignment can delete or add on extra chunks of DNA within the chromosome.

“Normally, a deletion like this would be detrimental,” Olsen said. “But when these genes are deleted, the plant is favored in certain environments, and so this morph is maintained. That’s why we see this polymorphism so often in natural populations.”

It’s not that evolution, restarted, would repeat itself exactly, Olsen said. But the closer the evolutionary relationship between species, the more likely there will be underlying predispositions that make the same traits pop up repeatedly in the same way.

In some ways, these predispositions are analogous to the crease patterns in origami paper that make it easier to fold the paper into some shapes than others. Evolution can fold across a crease — but it is much easier to fold along one.



Poet Mary Jo Bang receives Berlin Prize Fellowship

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Bang
Award-winning poet Mary Jo Bang, professor of English in Arts & Sciences at Washington University in St. Louis, is one of 25 recipients of a 2014-15 Berlin Prize Fellowship.

The American Academy in Berlin awards the highly competitive prize annually to scholars, writers and artists who represent the highest standards of excellence in their fields. 

The Berlin Prize includes a monthly stipend, partial board and residence at the academy’s lakeside Hans Arnhold Center in Berlin-Wannsee for either the fall 2014 or spring 2015 term.

Bang, who is the 2008 National Book Critics Circle Award winner in poetry, will be part of the spring 2015 class. She plans to work on a book of poems, titled “The Bauhaus: A Study in Balance."

For more on the prize, visit here.



Those with episodic amnesia are not ‘stuck in time,’ says philosopher Carl Craver

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In 1981, a motorcycle accident left Toronto native Kent Cochrane with severe brain damage and dramatically impaired episodic memory. Following the accident, Cochrane could no longer remember events from his past. Nor could he predict specific events that might happen in the future.

When neuroscientist Endel Tulving, PhD, asked him to describe what he would do tomorrow, Cochrane could not answer and described his state of mind as “blank.”

Psychologists and neuroscientists came to know Cochrane, who passed away earlier this year, simply as “KC.” Many scientists have described KC as “stuck in time,” or trapped in a permanent present.

It has generally been assumed that people with episodic amnesia experience time much differently than those with more typical memory function. 

However, a recent paper in Neuropsychologia co-authored by Carl F. Craver, PhD, professor of philosophy and of philosophy-neuroscience-psychology, both in Arts & Sciences at Washington University in St. Louis, disputes this type of claim.

“It’s our whole way of thinking about these people that we wanted to bring under pressure,” Craver said. “There are sets of claims that sound empirical, like ‘These people are stuck in time.’ But if you ask, ‘Have you actually tested what they know about time?’ the answer is no.”

Time and consciousness

A series of experiments convinced Craver and his co-authors that although KC could not remember specific past experiences, he did in fact have an understanding of time and an appreciation of its significance to his life.

Interviews with KC by Craver and his colleagues revealed that KC retained much of what psychologists refer to as “temporal consciousness.” KC could order significant events from his life on a timeline, and he seemed to have complete mastery of central temporal concepts.

Craver
For example, KC understood that events in the past have already happened, that they influence the future, and that once they happen, they cannot be changed. 

He also knew that events in the future don’t remain in the future, but eventually become present. Even more interestingly, KC’s understanding of time influenced his decision-making.

If KC truly had no understanding of time, Craver argues, then he and others with his type of amnesia would act as if only the present mattered. Without understanding that present actions have future consequences or rewards, KC would have based his actions only upon immediate outcomes. However, this was not the case.

On a personality test, KC scored as low as possible on measures of hedonism, or the tendency to be a self-indulgent pleasure-seeker.

In systematic tests of his decision-making, carried out with WUSTL’s Len Green, PhD, professor of psychology, and Joel Myerson, PhD, research professor of psychology, and researchers at York University in Toronto, KC also showed that he was willing to trade a smaller, sooner reward for a larger, later reward.

In other words, KC’s inability to remember past events did not affect his ability to appreciate the value of future rewards. 

‘Questions are now wide open’

KC’s case reveals how much is left to discover about memory and how it relates to human understanding of time.

“If you think about memory long enough it starts to sound magical,” Craver said. “How is it that we can replay these events from our lives? And what’s going on in our brains that allows us to re-experience these events from our past?”

Craver hopes that this article — the last to be published about KC during his lifetime — brings these types of questions to the forefront. 

“These findings open up a whole new set of questions about people with amnesia,” Craver said. “Things that we previously thought were closed questions are now wide open.”

The study, “Individuals with episodic amnesia are not stuck in time,” was co-authored with York University’s Donna Kwan and R. Shayna Rosenbaum, PhD; and Chloe Steindam, a former undergraduate student of Craver’s who graduated from WUSTL in 2013. The article appeared in Neuropsychologia on March 26, 2014.



Insect diet helped early humans build bigger brains, study suggests

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A. Melin
A capuchin monkey of the Cebus variety dines on a bright green katydid grasshopper. A steady diet of abundant ripe fruit and leaf-crawling insects may explain why Cebus can't hold a stick to their Sapajus capuchin cousins when it comes to tool usage and other higher-level cognitive skills. 
Figuring out how to survive on a lean-season diet of hard-to-reach ants, slugs and other bugs may have spurred the development of bigger brains and higher-level cognitive functions in the ancestors of humans and other primates, suggests research from Washington University in St. Louis.

“Challenges associated with finding food have long been recognized as important in shaping evolution of the brain and cognition in primates, including humans,” said Amanda D. Melin, PhD, assistant professor of anthropology in Arts & Sciences and lead author of the study.

Melin
“Our work suggests that digging for insects when food was scarce may have contributed to hominid cognitive evolution and set the stage for advanced tool use.”

Based on a five-year study of capuchin monkeys in Costa Rica, the research provides support for an evolutionary theory that links the development of sensorimotor (SMI) skills, such as increased manual dexterity, tool use, and innovative problem solving, to the creative challenges of foraging for insects and other foods that are buried, embedded or otherwise hard to procure.

Published in the June 2014 Journal of Human Evolution, the study is the first to provide detailed evidence from the field on how seasonal changes in food supplies influence the foraging patterns of wild capuchin monkeys.

The study is co-authored by biologist Hilary C. Young and anthropologists Krisztina N. Mosdossy and Linda M. Fedigan, all from the University of Calgary, Canada.

It notes that many human populations also eat embedded insects on a seasonal basis and suggests that this practice played a key role in human evolution.

“We find that capuchin monkeys eat embedded insects year-round but intensify their feeding seasonally, during the time that their preferred food – ripe fruit – is less abundant," Melin said. "These results suggest embedded insects are an important fallback food.”

Previous research has shown that fallback foods help shape the evolution of primate body forms, including the development of strong jaws, thick teeth and specialized digestive systems in primates whose fallback diets rely mainly on vegetation.

A. Melin
Melin has been investigating the visual and foraging ecology of white-faced capuchins in the tropical dry forests of Guanacas, Costa Rica, since 2004.
This study suggests that fallback foods can also play an important role in shaping brain evolution among primates that fall back on insect-based diets, and that this influence is most pronounced among primates that evolve in habitats with wide seasonal variations, such as the wet-dry cycles found in some South American forests.

“Capuchin monkeys are excellent models for examining evolution of brain size and intelligence for their small body size, they have impressively large brains,” Melin said. “Accessing hidden and well-protected insects living in tree branches and under bark is a cognitively demanding task, but provides a high-quality reward: fat and protein, which is needed to fuel big brains.”

But when it comes to using tools, not all capuchin monkey strains and lineages are created equal, and Melin’s theories may explain why.

Perhaps the most notable difference between the robust (tufted, genus Sapajus) and gracile (untufted, genus Cebus) capuchin lineages is their variation in tool use. While Cebus monkeys are known for clever food-foraging tricks, such as banging snails or fruits against branches, they can’t hold a stick to their Sapajus cousins when it comes to the
innovative use and modification of sophisticated tools.

One explanation, Melin said, is that Cebus capuchins have historically and consistently occupied tropical rainforests, whereas the Sapajus lineage spread from their origins in the Atlantic rainforest into drier, more temperate and seasonal habitat types.

“Primates who extract foods in the most seasonal environments are expected to experience the strongest selection in the 'sensorimotor intelligence' domain, which includes cognition related to object handling,” Melin said. “This may explain the occurrence of
tool use in some capuchin lineages, but not in others.”

Genetic analysis of mitochondial chromosomes suggests that the Sapajus-Cebus diversification occurred millions of years ago in the late Miocene epoch.

E. Visalberghi
An adult female tufted capuchin monkey of the Sapajus lineage using a stone tool and a sandstone anvil to crack a palm nut as her infant hangs on.

“We predict that the last common ancestor of Cebus and Sapajus had a level of SMI more closely resembling extant Cebus monkeys, and that further expansion of SMI evolved in the robust lineage to facilitate increased access to varied embedded fallback foods,
necessitated by more intense periods of fruit shortage,” she said.

One of the more compelling modern examples of this behavior, said Melin, is the seasonal consumption of termites by chimpanzees, whose use of tools to extract this protein-rich food source is an important survival technique in harsh environments.

Melin's study appears in a June 2014 special issue of the Journal of Human Evolution.
What does this all mean for hominids?

While it’s hard to decipher the extent of seasonal dietary variations from the fossil record, stable isotope analyses indicate seasonal variation in diet for at least one South African hominin, Paranthropus robustus. Other isotopic research suggests that early human diets may have included a range of extractable foods, such as termites, plant roots and tubers.

Modern humans frequently consume insects, which are seasonally important when other animal foods are limited.

This study suggests that the ingenuity required to survive on a diet of elusive insects has been a key factor in the development of uniquely human skills:

It may well have been bugs that helped build our brains.

To read the full study, click here.




Slaying bacteria with their own weapons

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The Centers for Disease Control and Prevention warned last fall that the U.S. faces “potentially catastrophic consequences” if it doesn’t act quickly to combat the growing threat of antibiotic-resistant infections, which kill about 23,000 Americans a year.

Timothy Wencewicz, PhD, assistant professor of chemistry in Arts & Science at Washington University in St. Louis, has an idea that might provide a solution to resistance that is broader and more effective than the invention of a new drug.

“Today when you walk in with the symptoms of a bacterial infection,” Wencewicz said, “you are treated with a broad-spectrum antibiotic because we lack the ability to identify a bacterial strain quickly. And that means every type of bacteria in your body is exposed to that antibiotic.” So even justified antibiotic use that follows medical protocols encourages resistance.

One solution, he said, is personalized antibiotic therapy. This would require both rapid bacterial identification and narrow-spectrum antibiotics. Tailored antibiotic therapy would not only extend the clinical lifetime of new antibiotics by better managing resistance, it might also revive old antibiotics that have been abandoned due to resistance, toxicity, or their inability to penetrate bacterial membranes.

Wencewicz is working on a drug delivery system that would target specific bacteria by exploiting small molecules called siderophores they secrete to scavenge for iron in their environment. Each bacterium has its own system of siderophores, which it pumps across its cell membrane before cleaving off the iron. 

 generated using PDB file 4K19 (Allred, B. E.; Correnti, C.; Clifton, M. C.; Strong, R. K.; Raymond, K. N. ACS Chemical Biology 2013, 8, 1882-1887).
A siderophore called fluvibactin made by the bacterium Vibrio cholera (blue structure) that has bound an iron atom (pink sphere).

If an antibiotic were linked to one of these scavenger molecules, it could be converted into a tiny Trojan horse that would smuggle antibiotics inside the bacterium’s cell membrane. Not only would the bacterium be directed against a specific pathogen, it would be effective at much lower concentrations because it would have penetrated the bacterium’s outer defenses.

What’s more, because each bacterial species has its own siderophore system, these molecules and their receptors could be used to rapidly identify the bacterial strain causing an infection. Siderophore diagnosis could be paired with siderophore drug delivery to provide personalized therapy that would spare patients trial-and-error treatment and, more importantly, make it much more difficult for bacteria to develop resistance.

Wencewicz has received a Ralph E. Powe Junior Faculty Enhancement Award from Oak Ridge Associated Universities (ORAU), a 114-member university consortium whose mission is to advance scientific knowledge, to systematically investigate a panel of 25 siderophores he synthesized while he was a graduate student at the University of Notre Dame. Using a laboratory strain of Staphylococcus aureus as a bioassay to test which ones work best, the goal is to lay the basis for rational siderophore-antibiotic drug design. 


So, it is to be war between us!
With billions of years of evolution at their backs, bacteria have developed mind-boggling survival skills. One of these is finding iron even in environments where it is present in insoluble forms or at very low concentrations.

Iron, Wencewicz explains, is essential for life and plays a role in many biological processes, including oxygen transport. Although iron is one of the most abundant elements in the Earth’s crust, most of it is in the iron(III) state—the most stable form of iron in an oxygenated environment—which is very insoluble and so essentially bio-unavailable.

“Bacteria have to scavenge the nutrient directly from insoluble iron minerals in the soil. And to do that they’ve evolved the ability to make these fascinating molecules called siderophores,” he said. Siderophores are iron chelators (from the Greek khele meaning “having pincer-like claws.”) “They grab onto iron, pull it off of the insoluble source and bring it into aqueous solution.” (See the video, above, for a demonstration.)

Because bacteria are competing for iron, Wencewicz said, there is pressure to evolve a siderophore no other bacterium can recognize and steal. More than 500 are known, but Wencewicz thinks there are probably tens of thousands that haven’t yet been found. Each bacterium has receptors in its cell membrane that recognize its own siderophore, which it then pumps inside its membrane.

Sometimes this works and sometimes it doesn’t. “Bacteria are very clever, “ Wencewicz said, and “they’ve evolved to steal siderophores from other bacteria by stealing their DNA and expressing the protein coded by the DNA. There are bacteria out there that maybe make only one siderophore, but they can recognize 10 and transport them across their cell membranes. They make their buddies do the work.”

Bacteria also confront a hostile iron-poor environment when they invade our bodies. Free iron is toxic so almost all of the iron in our bodies is bound to proteins, such as hemoglobin (in red blood cells) and the less familiar ferritin (inside cells) and transferrin (circulating in our blood).

So once insider our bodies, infecting bacteria make and secrete their siderophores, looking for iron. Some of them can also pry open our iron-storing proteins and break into cells to get at the iron sequestered there.

Generated using PDB file 4K19 (Allred, B. E.; Correnti, C.; Clifton, M. C.; Strong, R. K.; Raymond, K. N. ACS Chemical Biology 2013, 8, 1882-1887).
The siderophore fluvibactin sitting within the pocket of a siderocalin, which prevents it from delivering the iron it holds to the bacteria that secreted it.

We counter the siderophore onslaught by making molecules called siderocalins that bind siderophores, preventing them from binding iron. But some bacteria sidestep this defense, making a sacrificial siderophore that saturates the available siderocalin and a second “stealth” siderophore that siderocalin doesn’t recognize.

“Each pathogen is unique,” Wencewicz said. “If we are going to use its own siderophores against it, we have to understand each siderophore it secretes, its function, and how its function is related to its structure.

“We have to quit thinking that every single bacterium is like all the other bacteria. They’re not,” he said.


Beware of Greeks bearing gifts
Wencewicz’ central insight is that this specificity—and the fact that the bacteria bring siderophores inside their cell membranes—can be turned against them.

He is taking his cue from the bacteria themselves. Some bacteria, he said, link a toxic antibacterial agent to a siderophore, creating something called a sideromycin.

Competing bacteria, attempting to steal iron, grab the sideromycin and shuttle it in through their siderophore-uptake system. Once the sideromycin is inside the bacterium, the toxin it carries kills the bacterium.

Because the siderophore system is highly specific, Wencewicz believes it can be used to target even broad-spectrum antibiotics to individual bacterial strains, avoiding the indiscriminate exposures that spread resistance. And because the Trojan horse antibiotics will ferry antibiotic inside the membrane, only tiny doses will be needed. 

 generated using PDB file 4K19 (Allred, B. E.; Correnti, C.; Clifton, M. C.; Strong, R. K.; Raymond, K. N. ACS Chemical Biology 2013, 8, 1882-1887
A hypothetical Trojan horse drug might consist of a siderophore (blue) linked to an antibiotic, in this case the broad-spectrum antibiotic ciprofloxacin (green). Many bacteria have evolved resistance to ciprofloxacin in recent years, leaving it less effective than it once was. Attaching it to a siderophore might make the antibiotic useful again because bacteria pump siderophores inside their cell membranes where they can do maximum damage.

 

For both reasons he believes siderophore delivery systems will delay the emergence of resistance to new antibiotics and rescue many older antibiotics that have been abandoned because of resistance or toxicity.

Targeted therapy would be useless without rapid diagnostics because doctors wouldn’t know which sideromycin-like drug to prescribe. But because siderophore systems are specific to bacterial species, they could be used to type as well as to treat bacteria.

Because of resistance, we really need to discover new approaches to antibiotic development and not just continually re-jigger existing drugs, Wencewicz said. The siderophore pathway offers the opportunity to completely re-imagine antibiotic development so that it takes resistance into account up front instead of on the back end.





Jay Hutson & da Wolvez July 10

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San Francisco trumpeter Erik Jekabson will perform July 17 for WUSTL's free Jazz in July series.

In his 35 years as a renowned Los Angeles studio musician, saxophonist Jay Hutson has performed with everyone from Frankie Valli and Aretha Franklin to the Pointer Sisters and Sean “Puff Daddy” Combs.

At 8 p.m. Thursday, July 10, Hutson and his band da Wolvez will launch WUSTL’s Jazz in July series with a free performance at the Danforth University Center’s Tisch Commons.


Four concerts, four takes on jazz

A St. Louis native, Hutson studied music at Webster University and Southern Illinois University at Edwardsville before decamping for the west coast. Since returning home, in 2009, he has performed with local standouts like Kim Massie and the Soulard Blues Band. He’s also established da Wolvez, a St. Louis collective that performs contemporary jazz/funk.

Bill Lenihan, director of jazz performance, notes that each of the four Jazz in July performances will highlight a different jazz idiom. In addition to jazz/funk, the series will feature traditional jazz tunes, jazz standards and straight-ahead modern jazz.

“’Jazz standards’ refers to a body of repertoire composed or improvised by the Tin Pan Alley composers of the 1920s-40s and modern writers of the 1950s,” Lenihan says.

“Jazz/funk, jazz/rock and fusion describe extensions of 1960s 'acoustic' jazz practice and the use of newer rock and funk rhythms in the 1970s,” Lenihan adds. “’Straight-ahead jazz’ is an art historical term indicating the jazz of the middle periods, particularly late bebop and pop/modernism.”

Representing the latter, on July 17, will be San Francisco trumpeter Erik Jekabson and his band. Guitarist Dave Black and vocalist Joe Mancuso will join forces for an evening of traditional jazz tunes July 24.

Concluding the series, July 31, will be an evening of jazz standards from pianist Kara Baldus, bassist Eric Stiller and drummer Kyle Honeycutt. Baldus, who teaches piano in the WUSTL jazz program, is one-half of the electro-pop duo Dropkick the Robot, which recently took the award for best electronic song in the 2014 John Lennon Songwriting Contest.


Jazz at Holmes

Jazz in July is organized by Jazz at Holmes, which presents free campus concerts in a coffee-house setting most Thursdays throughout the year.

All Jazz in July performances take place from 8 to 10 p.m. The Danforth University Center is located at 6475 Forsyth Blvd. For more information, call (314) 862-0874; email staylor@wustl.edu; or visit Jazz at Holmes on Facebook.

Jazz at Holmes is sponsored by Arts and Sciences, Student Union, Congress of the South 40, the Department of Music, University College and Summer School, Campus Life, Danforth University Center and Event Management, Community Service Office, Office of Student Involvement and Leadership, Greek Life Office and the Office of Residential Life.



Washington University’s Joseph Jez is one of 15 ‘million dollar professors’

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Joe angeles/WUSTL Photos
Newly designated HHMI Professor Joseph Jez, PhD, an associate professor of biology in Arts & Sciences at Washington University in St. Louis, speaking with a student in the hallway.

 

Joseph Jez, PhD, co-director of the plant and microbial biosciences graduate program in Arts & Sciences at Washington University in St. Louis, is one of 15 professors nationwide to receive $1 million over the next five years to bring the creativity he has shown in the lab to the undergraduate classroom.

The Howard Hughes Medical Institute (HHMI) created the HHMI Professors Program in 2002 to empower research scientists to apply to science education the same creativity and rigor that made them successful in scientific research. 

In the past 12 years, 40 scientists have been appointed HHMI professors, receiving grants to support innovation in undergraduate science education.

In the current competition, which opened in April 2013, HHMI invited 106 research universities classified by the Carnegie Foundation for the Advancement of Teaching as having “very high research activity” to nominate faculty members.

A panel of scientists and educators reviewed 173 nominees’ proposals and eventually selected 15 HHMI Professors at 13 universities. 

HHMI announced the selections in a June 30 news release

Jez, associate professor of biology in Arts & Sciences, studies the molecular basis of biological processes in plants, microbes and nematodes. 

He plans to use the HHMI grant to launch a two-year program in fall 2016. Called the Biotech Explorers Pathway, it will introduce entering students to both the science and business of biotechnology.

“Within my research group and in my courses,” Jez said, “I often draw on my experiences in biotech as an undergraduate in a professor’s start-up and later as a scientist at an established company to capture the imagination of students by helping them understand how discovery leads to application.”

In their first year of the Biotech Explorers Pathway, students will develop science-based case studies of St. Louis biotech companies and participate in seminars led by founders and directors of local companies. 

They will have the opportunity to practice job interviews with scientists and managers from those companies.

“Lectures and textbooks fall short of providing insight into the challenges of converting ideas to real-world products,” Jez said. “But this class will bring in people from the St. Louis biotech community to share their experiences and perspectives with the students.”

In the second year of the Biotech Explorers Pathway, teams of four students led by a graduate student or postdoctoral associate will generate project ideas and write them up as proposals, ultimately preparing two-minute elevator pitches for their projects. 

The class will identify the top five project pitches, which then will be polished in the second semester and ultimately presented to a review panel. Students completing the Pathway will be eligible for summer fellowships to smooth their transition to capstone experiences.

Remarkably, Jez hopes to pull in students interested not just in science and engineering but also in business. “The long-term goal of the Biotech Explorers Pathway,” he said, “is to train the next generation of science and business leaders and to provide a model for transmitting the excitement and value of scientific research to undergraduate students.”

In addition to establishing the Biotech Explorers Pathway, Jez will use the HMMI funds to support undergraduate research teams in his own lab and in an upper-level laboratory course he has developed where teams of students work on research questions that turn on protein structure and function.

Team-based approach

Jez has served as a mentor to more than 60 students either in his own lab or through the WUSTL International Genetically Engineered Machine (iGEM) team, which competes in an international competition in synthetic biology. Nearly all of these students have continued in science and technology after graduation.

Jez credits this success in part to a team-based approach to research. Typically in his lab two to four students work with an advanced student who serves as a peer-mentor. A graduate student or postdoctoral associate, and Jez himself, periodically review the team’s progress. 

The team-based approach reduces the lack of continuity introduced by the academic calendar, gives advanced students practice with teaching and mentoring, and provides younger students with a role model for undergraduate research.

Finally, the HHMI grant will help support a lab course in protein chemistry Jez developed in 2010. Each year, the students in this extremely popular course frame a problem related to protein function that emerges from research in a WUSTL lab. They plan a series of experiments to solve the problem. The experiments are then divided up among work groups in the class.

As in Jez’s other initiatives, undergraduates are treated as full participants in the research endeavor. “Students overwhelmingly value projects that lead to the generation of scientific knowledge and allow them to develop their own ideas and become intellectual entrepreneurs,” Jez said.

Jez is the second WUSTL faculty member to be named an HHMI Professor. Sarah C. R. Elgin, PhD, the Viktor Hamburger Professor of Arts & Sciences, was in the inaugural group of professors chosen in 2002. 

With HHMI funding, Elgin has established the Genomics Education Partnership that gives students an opportunity to do original research by participating in a large-scale genome sequencing and annotation research project. For more information about her educational initiatives and to read her HHMI biography, visit here.



Doctoral students to study biology, mechanics connection under NIH grant

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Petr Novák/Wikimedia Commons
The Venus Flytrap is one of nature's best examples of the integration of mechanics and biology, known as mechanobiology.

The Venus Flytrap is a fascinating plant with two leaf jaws that sense when an insect approaches and quickly snap shut, trapping the insect for a meal. The carnivorous plant is one of nature’s clearest examples of biology and mechanics working together to sustain life.

Four doctoral students at Washington University in St. Louis will have the opportunity to take a closer look at this intersection under a five-year, $921,040 grant from the National Institute of Biomedical Imaging and Bioengineering of the National Institutes of Health.

Philip V. Bayly, PhD, the Lilyan and E. Lisle Hughes Professor of Mechanical Engineering and chair of the Department of Mechanical Engineering & Materials Science, will lead the grant to train four doctoral students in mechanobiology, a developing field that focuses on how forces and changes in cell or tissue mechanical properties contribute to growth, structure and health.

More than 25 faculty members from across the university will serve as mentors to the four students.

Bayly
“This training grant is unique because we have pure biologists from the Department of Biology, as well as biologists in the School of Medicine who apply biology to medicine,” Bayly said. “There are a lot of people who already involve mechanics in biological research. This is a nice opportunity because it brings them together and provides an opportunity for students to work in those interfaces.”

Blending biology with engineering and other scientific disciplines, such as physics, chemistry, computer science and math, is part of “A New Biology for the 21st Century” initiative by the National Research Council of the National Academies. The initiative is designed to integrate these disciplines to create a research community that can tackle a broad range of scientific problems.

Bayly said students in this program will be prepared to perform advanced, interdisciplinary research on the role of mechanics in biology and will fill an important and growing need in the scientific community.

The Washington University students who train under the grant will cross disciplines: those who are studying biology will take basic courses in mechanical engineering, and engineering students will take basic biology courses.

In addition, students will conduct research on a variety of length scales, from the tiniest (nanometer) to larger sizes, corresponding to structures from the molecular and cellular level to the tissue level. They will also to spend eight to 10 hours a year doing outreach activities with high school or younger students.

“Outreach helps students develop teaching and communication skills,” Bayly said. “One of the best ways for Washington University to be a good member of the community is to take all of this intellectual horsepower we have in our students and bring it to bear in St. Louis.”


 The School of Engineering & Applied Science at Washington University in St. Louis focuses intellectual efforts through a new convergence paradigm and builds on strengths, particularly as applied to medicine and health, energy and environment, entrepreneurship and security. With 82 tenured/tenure-track and 40 additional full-time faculty, 1,300 undergraduate students, 700 graduate students and more than 23,000 alumni, we are working to leverage our partnerships with academic and industry partners — across disciplines and across the world — to contribute to solving the greatest global challenges of the 21st century.



STEM Faculty Institute on Teaching a good FIT

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article image

Sid Hastings/WUSTL Photos

Washington University in St. Louis’ Daniel E. Giammar, PhD (right), the Harold D. Jolley Career Development Associate Professor in energy, environmental and chemical engineering, and Mairin Hynes, PhD, lecturer in physics in Arts & Sciences, participate in WUSTL’s inaugural Summer STEM Faculty Institute on Teaching (STEM FIT). The institute, held June 17-19 in Seigle Hall, brought together 18 faculty from eight departments in Arts & Sciences and the School of Engineering & Applied Science to develop strategies for incorporating evidence-based teaching practices that can improve student learning and encourage undergraduates to persist in STEM majors. The Teaching Center developed and facilitated STEM FIT, with support from the Association of American Universities' STEM education initiative. Gina Frey, PhD, the center's executive director and the Florence E. Moog Professor of STEM Education, said the institute’s “goal was to establish a culture here where teaching is a shared and collaborative endeavor, not a solitary one. The approach advocated does not require a ‘one size fits all’ version of active learning, but instead relies on multiple and diverse strategies that can be effectively integrated with the faculty member’s existing learning objectives and style of teaching.”



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